SCHEMBL6975522

SCHEMBL6975522

CC(=O)NCC(=O)N(C)c1ccc(Cl)c(CO)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 11/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10072520 0.84 BDKRB2 (0.41) BDKRB2
SCHEMBL6972291 0.81 BDKRB2 (0.52) BDKRB2
SCHEMBL8477267 0.81 GABRP (0.46) BDKRB2
SCHEMBL6643301 0.78 BDKRB2 (0.68) BDKRB2
SCHEMBL6643303 0.78 BDKRB2 (0.68) BDKRB2
SCHEMBL6976001 0.77 BDKRB2 (0.64) BDKRB2
SCHEMBL6640293 0.76 BDKRB2 (0.64) BDKRB2
SCHEMBL6640288 0.76 BDKRB2 (0.64) BDKRB2
SCHEMBL6975133 0.75 BDKRB2 (0.51) BDKRB2
SCHEMBL8011822 0.73 BDKRB2 (0.59) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0900203-B1 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO (JP) 2003-03-19 EP disclosed
US-6083959-A BRADYKININ ANTAGONISTS; FOR THE PREVENTION AND/OR THE TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES SUCH AS ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-04 US disclosed
EP-0900203-A1 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-03-10 EP disclosed
WO-1997041104-A1 QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-06 WO disclosed