Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892807 | 0.86 | KCNH2 (0.48) | HCAR3ALDH1A1HTTPOLBMAPT | |
| SCHEMBL10892820 | 0.86 | KCNH2 (0.48) | HCAR3ALDH1A1HTTPOLBMAPT | |
| SCHEMBL9684999 | 0.86 | KCNH2 (0.48) | HCAR3ALDH1A1HTTPOLBMAPT | |
| SCHEMBL6978258 | 0.84 | HCAR3 (0.52) | HCAR3NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL27530717 | 0.82 | HCAR3 (0.47) | HCAR3NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL10435141 | 0.82 | KCNH2 (0.44) | ALDH1A1HTTPOLBMAPTSMN1; SMN2 | |
| SCHEMBL10888628 | 0.82 | KCNH2 (0.44) | ALDH1A1HTTPOLBMAPTSMN1; SMN2 | |
| SCHEMBL9743220 | 0.82 | KCNH2 (0.44) | ALDH1A1HTTPOLBMAPTSMN1; SMN2 | |
| SCHEMBL6975515 | 0.81 | HCAR3 (0.46) | HCAR3NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL6975503 | 0.81 | HCAR3 (0.46) | HCAR3NPC1RAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| CN-1226243-A | Benzodihydropyran derivative | NISSAN CHEMICAL IND LTD (JP) | 1999-08-18 | — | — | CN | disclosed |
| EP-0934296-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004542-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-05 | — | — | WO | disclosed |