Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13951737 | 0.86 | KCNH2 (0.42) | ALDH1A1HTTMAPTSMN1; SMN2POLB | |
| SCHEMBL6161775 | 0.86 | KCNH2 (0.42) | ALDH1A1HTTMAPTSMN1; SMN2POLB | |
| SCHEMBL12961840 | 0.86 | KCNH2 (0.42) | ALDH1A1HTTMAPTSMN1; SMN2POLB | |
| SCHEMBL14765557 | 0.86 | KCNH2 (0.42) | ALDH1A1HTTMAPTSMN1; SMN2POLB | |
| SCHEMBL6980817 | 0.85 | KCNH2 (0.56) | NPC1RAB9AMAPK1ALDH1A1HTT | |
| SCHEMBL6971457 | 0.85 | KCNH2 (0.41) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL6972374 | 0.84 | HCAR3 (0.51) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL6163980 | 0.83 | KCNH2 (0.47) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL6163946 | 0.82 | KCNH2 (0.44) | HCAR3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6982472 | 0.82 | KCNH2 (0.55) | MAPK1ALDH1A1MAPTSMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| CN-1226243-A | Benzodihydropyran derivative | NISSAN CHEMICAL IND LTD (JP) | 1999-08-18 | — | — | CN | disclosed |
| EP-0934296-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004542-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-05 | — | — | WO | disclosed |