Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.55 |
| ▸ | MMP3 | P08254 | 7/20 | 0.55 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 7/20 | 0.38 |
| ▸ | RAF1 | P04049 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956213 | 1.00 | MMP2 (0.55) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6433803 | 0.92 | MMP2 (0.52) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6433657 | 0.92 | MMP2 (0.52) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6434651 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6436315 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6434274 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6436812 | 0.92 | MMP2 (0.51) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6964593 | 0.90 | MMP2 (0.67) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6967923 | 0.88 | MMP2 (0.58) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6434543 | 0.86 | MMP2 (0.60) | MMP2MMP3MMP9MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |