Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.58 |
| ▸ | MMP3 | P08254 | 9/20 | 0.58 |
| ▸ | MMP9 | P14780 | 9/20 | 0.58 |
| ▸ | MMP14 | P50281 | 3/20 | 0.58 |
| ▸ | MMP1 | P03956 | 2/20 | 0.58 |
| ▸ | MMP13 | P45452 | 10/20 | 0.39 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964593 | 0.94 | MMP2 (0.67) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6433879 | 0.92 | MMP2 (0.55) | MMP2MMP3MMP9MMP14MMP1 | |
| Hydrochloric Acid SCHEMBL6434664 | 0.91 | MMP2 (0.54) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6434543 | 0.91 | MMP2 (0.60) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6956213 | 0.88 | MMP2 (0.55) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6972399 | 0.88 | MMP2 (0.55) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6439579 | 0.86 | MMP2 (0.62) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6968408 | 0.85 | MMP2 (0.67) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6433286 | 0.85 | MMP2 (0.64) | MMP2MMP3MMP9MMP14MMP1 | |
| SCHEMBL6956221 | 0.85 | MMP2 (0.68) | MMP2MMP3MMP9MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |