Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.67 |
| ▸ | MMP3 | P08254 | 9/20 | 0.67 |
| ▸ | MMP9 | P14780 | 8/20 | 0.67 |
| ▸ | MMP1 | P03956 | 3/20 | 0.67 |
| ▸ | MMP14 | P50281 | 2/20 | 0.67 |
| ▸ | MMP13 | P45452 | 10/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967923 | 0.94 | MMP2 (0.58) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6433286 | 0.92 | MMP2 (0.64) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6956221 | 0.92 | MMP2 (0.68) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6435284 | 0.92 | MMP2 (0.63) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6434543 | 0.92 | MMP2 (0.60) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6964678 | 0.91 | MMP2 (0.67) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6439579 | 0.91 | MMP2 (0.62) | MMP2MMP3MMP9MMP1MMP14 | |
| Hydrochloric Acid SCHEMBL6965337 | 0.91 | MMP2 (0.66) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6956213 | 0.90 | MMP2 (0.55) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6972399 | 0.90 | MMP2 (0.55) | MMP2MMP3MMP9MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030099693-A1 | Wafer | PFIZER INC. | 2003-05-29 | — | — | US | claimed |
| WO-2003037395-A1 | WAFER FOR WOUNDS | PFIZER LIMITED (GB) | 2003-05-08 | — | — | WO | claimed |
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |
| US-20030099693-A1 | Wafer | PFIZER INC. | 2003-05-29 | — | — | US | disclosed |