Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16312724 | 0.76 | MAPT (0.43) | NPC1MAPTHTTRAB9ANPSR1 | |
| SCHEMBL97740 | 0.73 | — | — | |
| SCHEMBL6972687 | 0.73 | CA12 (0.36) | — | |
| SCHEMBL7405360 | 0.71 | FFAR1 (0.33) | — | |
| SCHEMBL10716988 | 0.71 | — | — | |
| SCHEMBL28235092 | 0.70 | — | — | |
| SCHEMBL6219628 | 0.69 | ALDH1A1 (0.39) | RAB9A | |
| SCHEMBL2571596 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL8155628 | 0.68 | MAOA (0.34) | MAPT | |
| SCHEMBL28938346 | 0.68 | FFAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |