Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504745 | 0.86 | PPARA (0.49) | MMP8ALDH1A1CYP3A4POLBPPARA | |
| SCHEMBL2553482 | 0.86 | PPARA (0.49) | MMP8ALDH1A1CYP3A4POLBPPARA | |
| SCHEMBL17653645 | 0.86 | PPARA (0.49) | MMP8ALDH1A1CYP3A4POLBPPARA | |
| SCHEMBL13491149 | 0.85 | ALDH1A1 (0.47) | MMP8ALDH1A1CYP3A4POLBPPARA | |
| SCHEMBL16672673 | 0.83 | MMP8 (0.54) | MMP8ALDH1A1KMT2ALMNATSHR | |
| SCHEMBL5322346 | 0.83 | ALDH1A1 (0.46) | MMP8ALDH1A1CYP3A4POLBPPARA | |
| SCHEMBL17653672 | 0.83 | MMP8 (0.54) | MMP8ALDH1A1KMT2ALMNATSHR | |
| SCHEMBL17536560 | 0.83 | SMN1; SMN2 (0.44) | MMP8ALDH1A1CYP3A4POLBPPARA | |
| SCHEMBL27652260 | 0.83 | MMP8 (0.54) | MMP8ALDH1A1KMT2ALMNATSHR | |
| SCHEMBL16672466 | 0.81 | KMT2A (0.56) | MMP8ALDH1A1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |