Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973410 | 0.94 | LMNA (0.41) | LMNATLR7 | |
| SCHEMBL6962251 | 0.87 | TDP1 (0.38) | LMNATLR7 | |
| SCHEMBL6969647 | 0.82 | TLR7 (0.42) | TLR7PPARG | |
| SCHEMBL6962178 | 0.80 | LMNA (0.40) | LMNATLR7PPARG | |
| SCHEMBL6975529 | 0.79 | LMNA (0.41) | LMNATLR7PPARG | |
| SCHEMBL6971875 | 0.78 | LMNA (0.41) | LMNATLR7PPARG | |
| SCHEMBL7082248 | 0.78 | LMNA (0.40) | LMNATLR7PPARG | |
| SCHEMBL6968903 | 0.77 | MEN1 (0.43) | LMNA | |
| SCHEMBL6971258 | 0.76 | LMNA (0.40) | LMNATLR7 | |
| SCHEMBL6968991 | 0.74 | LMNA (0.41) | LMNATLR7PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |