Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969776 | 0.83 | TDP1 (0.40) | HSD17B10KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL129259 | 0.81 | LMNA (0.48) | HSD17B10KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL6670309 | 0.81 | KMT2A (0.40) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL14814745 | 0.81 | ELANE (0.51) | KDM4EALDH1A1 | |
| SCHEMBL5396445 | 0.80 | ACHE (0.43) | HSD17B10KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL9817182 | 0.80 | ELANE (0.49) | KMT2AMEN1LMNA | |
| SCHEMBL6292065 | 0.80 | NCEH1 (0.40) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8500041 | 0.78 | ELANE (0.36) | — | |
| SCHEMBL4260342 | 0.76 | RAB9A (0.57) | KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL128694 | 0.76 | ACHE (0.49) | HSD17B10KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | claimed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |