Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968454 | 0.92 | ENPP2 (0.39) | ENPP2CYP11B1CYP11B2KDM4ETP53 | |
| SCHEMBL6968985 | 0.90 | KDM4E (0.38) | ENPP2CYP11B1CYP11B2KDM4EP2RX3 | |
| SCHEMBL8343038 | 0.90 | TBXA2R (0.42) | ENPP2TBXA2R | |
| SCHEMBL6968962 | 0.88 | CYP11B1 (0.41) | ENPP2CYP11B1CYP11B2KDM4ECCNC | |
| SCHEMBL6968461 | 0.86 | CYP11B1 (0.31) | CYP11B1CYP11B2KDM4E | |
| SCHEMBL7085356 | 0.86 | ENPP2 (0.36) | ENPP2MAPK14 | |
| SCHEMBL6969213 | 0.85 | ENPP2 (0.35) | ENPP2CYP11B1TP53POLBP2RX3 | |
| SCHEMBL6974458 | 0.85 | S1PR3 (0.38) | ENPP2KDM4E | |
| SCHEMBL6967988 | 0.85 | ENPP2 (0.35) | ENPP2TP53POLBP2RX3 | |
| SCHEMBL7082084 | 0.84 | ENPP2 (0.35) | ENPP2TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |