Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969774 | 0.94 | ENPP2 (0.35) | ENPP2MAPK14GSK3BHPGD | |
| SCHEMBL6960983 | 0.92 | ENPP2 (0.32) | ENPP2HPGDMEN1KMT2A | |
| SCHEMBL6975612 | 0.91 | GRIN1 (0.35) | ENPP2MAPK14GSK3BKMT2A | |
| SCHEMBL6964205 | 0.91 | HRH1 (0.32) | ENPP2MAPK14MEN1KMT2A | |
| SCHEMBL6974234 | 0.91 | TDP1 (0.36) | ENPP2 | |
| SCHEMBL6974036 | 0.90 | ENPP2 (0.33) | ENPP2GSK3B | |
| SCHEMBL6966608 | 0.89 | MAPK14 (0.37) | ENPP2MAPK14GSK3B | |
| SCHEMBL6957360 | 0.89 | ENPP2 (0.33) | ENPP2 | |
| SCHEMBL6969945 | 0.88 | KCNH2 (0.34) | ENPP2GSK3BMEN1KMT2A | |
| SCHEMBL6972780 | 0.88 | MEN1 (0.33) | ENPP2GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |