Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 13/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344784 | 0.90 | LMNA (0.38) | S1PR3ENPP2ALDH1A1KDM4E | |
| SCHEMBL6973716 | 0.90 | HSP90AA1 (0.36) | S1PR3ENPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL6973417 | 0.86 | MAPT (0.37) | ENPP2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL6967358 | 0.86 | S1PR3 (0.35) | S1PR3ALDH1A1KDM4E | |
| SCHEMBL6972492 | 0.85 | S1PR3 (0.38) | S1PR3ALDH1A1KDM4E | |
| SCHEMBL6972660 | 0.85 | ENPP2 (0.40) | ENPP2KDM4E | |
| SCHEMBL6973222 | 0.85 | S1PR3 (0.41) | S1PR3ALDH1A1 | |
| SCHEMBL6973869 | 0.85 | TLR7 (0.35) | S1PR3ALDH1A1KDM4E | |
| SCHEMBL6969106 | 0.85 | HRH1 (0.36) | S1PR3 | |
| SCHEMBL6973511 | 0.84 | S1PR3 (0.36) | S1PR3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |