Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 9/20 | 0.32 |
| ▸ | CTSB | P07858 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968196 | 0.89 | CTSS (0.34) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5367852 | 0.89 | CTSS (0.40) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5360978 | 0.81 | CTSL (0.34) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6973197 | 0.79 | CTSS (0.43) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5357799 | 0.78 | CTSS (0.33) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5367860 | 0.77 | CTSS (0.46) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5366731 | 0.73 | CTSS (0.33) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5361368 | 0.73 | CTSS (0.42) | CTSSCTSL | |
| SCHEMBL7690161 | 0.72 | CTSK (0.37) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4250590 | 0.71 | CTSS (0.50) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | disclosed |