Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 15/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969906 | 0.84 | MGLL (0.64) | MGLLMEN1KMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL6979800 | 0.83 | MGLL (0.63) | MGLLMEN1KMT2AHSD11B1 | |
| SCHEMBL6969303 | 0.82 | POLB (0.60) | MGLLHSD11B1 | |
| Hydrochloric Acid SCHEMBL6969837 | 0.81 | POLB (0.59) | MGLLHSD11B1 | |
| SCHEMBL1720910 | 0.80 | MGLL (1.00) | MGLLMEN1KMT2AMAPTHSD11B1 | |
| SCHEMBL6208966 | 0.80 | MGLL (1.00) | MGLLMEN1KMT2AMAPTHSD11B1 | |
| SCHEMBL30590434 | 0.80 | RECQL (0.56) | MGLLMEN1KMT2A | |
| SCHEMBL2471282 | 0.80 | RECQL (0.56) | MGLLMEN1KMT2A | |
| SCHEMBL11754253 | 0.79 | HRH4 (0.54) | MGLL | |
| Hydrochloric Acid SCHEMBL9115524 | 0.78 | RECQL (0.54) | MGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5948786-A | BLOCKING TUMOR NECROSIS FACTOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |