Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | GLP1R | P43220 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962332 | 0.87 | LOXL2 (0.39) | HTR6GLP1RLOXL2CCR2CCR5 | |
| SCHEMBL27394329 | 0.86 | KMT2A (0.32) | HTR6CCR2CCR5 | |
| SCHEMBL6972384 | 0.86 | SMN1; SMN2 (0.32) | LOXL2 | |
| SCHEMBL27397435 | 0.83 | ANXA2 (0.33) | HTR6GLP1R | |
| SCHEMBL27421125 | 0.81 | KMT2A (0.32) | HTR6CCR2CCR5 | |
| SCHEMBL27407951 | 0.80 | POLB (0.43) | — | |
| SCHEMBL27392547 | 0.79 | LMNA (0.34) | HTR6GCGR | |
| SCHEMBL27412946 | 0.79 | POLB (0.37) | — | |
| SCHEMBL27537370 | 0.78 | POLB (0.36) | GCGR | |
| SCHEMBL27412965 | 0.77 | POLB (0.35) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |