Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.32 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | FKBP2 | P26885 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | FKBP1B | P68106 | 1/20 | 0.30 |
| ▸ | FKBP3 | Q00688 | 1/20 | 0.30 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969433 | 0.93 | KMT2A (0.38) | PIK3CDALDH1A1AGTR1NOX4ALOX5AP | |
| SCHEMBL7086006 | 0.89 | ALOX5AP (0.33) | PIK3CDALDH1A1ALOX5APATMAR | |
| SCHEMBL6960816 | 0.89 | S1PR3 (0.33) | ALDH1A1ALOX5APATMARKDM4E | |
| SCHEMBL6974447 | 0.87 | MEN1 (0.34) | PIK3CDHSP90B1TRAP1ALDH1A1AGTR1 | |
| SCHEMBL6976953 | 0.87 | ALDH1A1 (0.33) | HSP90B1TRAP1ALDH1A1AGTR1NOX4 | |
| SCHEMBL6975001 | 0.87 | ALDH1A1 (0.33) | PIK3CDHSP90B1TRAP1ALDH1A1AGTR1 | |
| SCHEMBL6969004 | 0.85 | CYP1A2 (0.33) | PIK3CDHSP90B1TRAP1ALDH1A1AGTR1 | |
| SCHEMBL7082531 | 0.85 | HRH1 (0.34) | HSP90B1TRAP1ALDH1A1AGTR1NOX4 | |
| SCHEMBL7082928 | 0.85 | HRH1 (0.36) | PIK3CDHSP90B1TRAP1ALDH1A1AGTR1 | |
| SCHEMBL6960568 | 0.85 | GRIN1 (0.37) | ALDH1A1NOX4ALOX5APATMAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |