Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ATP4A | P20648 | 2/20 | 0.37 |
| ▸ | ATP4B | P51164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415541 | 0.81 | MAOB (0.50) | RIPK1MAOBADORA2AALDH1A1ADORA2B | |
| SCHEMBL8818596 | 0.78 | NUDT1 (0.47) | ATP4AATP4BALDH1A1PARP1DAO | |
| SCHEMBL6984307 | 0.78 | MGAM (0.49) | GAAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL4364877 | 0.78 | ADORA2A (0.50) | RIPK1MAOBADORA2AKDM4EALDH1A1 | |
| SCHEMBL2899660 | 0.76 | DDAH1 (0.55) | ADORA2AGAAKDM4EALDH1A1ADORA1 | |
| SCHEMBL5788740 | 0.76 | PARP1 (0.54) | ATP4AATP4BKDM4EALDH1A1PARP1 | |
| SCHEMBL10835909 | 0.75 | DAO (0.38) | ATP4AATP4BKDM4EALDH1A1PARP1 | |
| SCHEMBL21855798 | 0.75 | ADORA1 (0.56) | MAOBADORA2AGAAKDM4EALDH1A1 | |
| SCHEMBL6582523 | 0.72 | DDAH1 (0.42) | ATP4AATP4BKDM4EALDH1A1DAO | |
| SCHEMBL6681270 | 0.72 | CHEK1 (0.45) | KDM4EALDH1A1PARP1DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286987-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung (AT) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094340-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | INNOVATIONSAGENTUR GESELLSCHAFT M.B.H. (AT) | 2001-12-13 | — | — | WO | disclosed |