Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973599 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BF2PLGTGFBR1 | |
| SCHEMBL6976329 | 0.94 | F2 (0.44) | ITGB3ITGA2BF2PLGTGFBR1 | |
| SCHEMBL6977329 | 0.93 | TGFBR1 (0.43) | ITGB3ITGA2BTGFBR1MMP13KDM4E | |
| SCHEMBL6977326 | 0.93 | TGFBR1 (0.43) | ITGB3ITGA2BTGFBR1MMP13KDM4E | |
| SCHEMBL6971755 | 0.90 | F2 (0.46) | ITGB3ITGA2BF2PLGTGFBR1 | |
| SCHEMBL6969381 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BF2PLGTGFBR1 | |
| SCHEMBL6976118 | 0.89 | F2 (0.44) | ITGB3ITGA2BF2PLGTGFBR1 | |
| SCHEMBL6971548 | 0.89 | F2 (0.43) | ITGB3ITGA2BF2PLGTGFBR1 | |
| SCHEMBL6975339 | 0.87 | MMP13 (0.44) | F2TGFBR1MMP13F10ST14 | |
| SCHEMBL7139133 | 0.87 | TGFBR1 (0.42) | F2TGFBR1MMP13F10ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |