Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697432 | 0.86 | TAAR1 (0.44) | P2RX7KMT2ATAAR1CTSS | |
| SCHEMBL698757 | 0.86 | KMT2A (0.43) | KMT2ATAAR1 | |
| SCHEMBL703867 | 0.84 | KMT2A (0.59) | P2RX7KMT2ATAAR1CTSSCTSK | |
| SCHEMBL696873 | 0.81 | KMT2A (0.55) | P2RX7KMT2ATAAR1 | |
| SCHEMBL698900 | 0.79 | KMT2A (0.46) | P2RX7KMT2ATAAR1 | |
| SCHEMBL27826873 | 0.77 | KMT2A (0.43) | KMT2ATAAR1 | |
| SCHEMBL697294 | 0.76 | KMT2A (0.37) | P2RX7KMT2ATAAR1 | |
| SCHEMBL697904 | 0.74 | KMT2A (0.42) | KMT2A | |
| SCHEMBL698190 | 0.73 | KMT2A (0.52) | P2RX7KMT2ATAAR1 | |
| SCHEMBL697349 | 0.71 | KMT2A (0.54) | P2RX7KMT2ATAAR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |