Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698757 | 0.88 | KMT2A (0.43) | TAAR1KMT2ANPC1RAB9A | |
| SCHEMBL697429 | 0.86 | P2RX7 (0.44) | TAAR1KMT2AP2RX7CTSS | |
| SCHEMBL697349 | 0.84 | KMT2A (0.54) | TAAR1KMT2AP2RX7AURKAAURKB | |
| SCHEMBL697904 | 0.82 | KMT2A (0.42) | KMT2ANPC1RAB9A | |
| SCHEMBL697294 | 0.78 | KMT2A (0.37) | TAAR1KMT2AP2RX7NPC1RAB9A | |
| SCHEMBL703857 | 0.75 | KMT2A (0.39) | TAAR1KMT2ANPC1RAB9ATAS1R3 | |
| SCHEMBL7235096 | 0.73 | TAAR1 (0.49) | TAAR1KMT2AP2RX7 | |
| SCHEMBL703867 | 0.72 | KMT2A (0.59) | TAAR1KMT2AP2RX7NPC1RAB9A | |
| SCHEMBL11266816 | 0.72 | KMT2A (0.47) | TAAR1KMT2ANPC1RAB9A | |
| SCHEMBL1573433 | 0.72 | KMT2A (0.37) | KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |