Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.40 |
| ▸ | WNT3A | P56704 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697432 | 0.88 | TAAR1 (0.44) | KMT2ATAAR1NPC1RAB9A | |
| SCHEMBL697429 | 0.86 | P2RX7 (0.44) | KMT2ATAAR1 | |
| SCHEMBL11266816 | 0.78 | KMT2A (0.47) | KMT2ATAAR1LMNACSNK1A1TYRO3 | |
| SCHEMBL697294 | 0.77 | KMT2A (0.37) | KMT2ATAAR1CSNK1A1TYRO3DYRK1B | |
| SCHEMBL697291 | 0.76 | KMT2A (0.46) | KMT2ATAAR1CTNNB1WNT3ACSNK1A1 | |
| SCHEMBL697904 | 0.75 | KMT2A (0.42) | KMT2ACSNK1A1TYRO3DYRK1BNPC1 | |
| SCHEMBL697349 | 0.72 | KMT2A (0.54) | KMT2ATAAR1CNR2NPC1RAB9A | |
| SCHEMBL703336 | 0.72 | NPC1 (0.44) | CNR2TLK2NPC1RAB9A | |
| SCHEMBL11137294 | 0.72 | NPC1 (0.42) | KMT2ACSNK1A1TYRO3DYRK1BNPC1 | |
| SCHEMBL697784 | 0.72 | MTOR (0.47) | KMT2ATAAR1GAACSNK1A1TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |