Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602394 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1KDM4EL3MBTL1ITGB1ITGA4 | |
| SCHEMBL4842646 | 0.74 | CYP1A2 (0.71) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL4909005 | 0.74 | SMN1; SMN2 (0.57) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL12577895 | 0.73 | ALDH1A1 (0.61) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL16838753 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL8422956 | 0.72 | NR4A2 (0.60) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL9129213 | 0.71 | MAOB (0.61) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL432927 | 0.71 | ALDH1A1 (0.57) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL2282797 | 0.71 | MAOB (0.61) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL23223734 | 0.71 | RAB9A (0.69) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095036-B1 | CINNAMIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH THERAPEUTICS LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-6465471-B1 | INHIBIT BINDING OF ALPHA 4 INTEGRINS TO THEIR LIGANDS THUS THEY ARE OF USE IN PROPHYLAXIS AND TREATMENT OF IMMUNE OR INFLAMMATORY DISORDERS | CELLTECH THERAPEUTICS LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |