SCHEMBL6974485

SCHEMBL6974485

CCS(=O)(=O)N(C(C)=O)c1cc(-n2nc(C(F)(F)F)n(C)c2=O)c(F)cc1C#N

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 18/20 0.37
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6699122 0.81 BCAT2 (0.33)
SCHEMBL6727299 0.78 GPR139 (0.33) DHODH
SCHEMBL6308458 0.78 PGR (0.40) DHODH
SCHEMBL6103445 0.77 DHODH (0.42) DHODHL3MBTL1
SCHEMBL7157679 0.77 PGR (0.39) DHODH
Potassium SCHEMBL7157685 0.77 PGR (0.39) DHODH
SCHEMBL7970802 0.77 DHODH (0.42) DHODHL3MBTL1
SCHEMBL6106477 0.75 DHODH (0.40) DHODH
SCHEMBL6175451 0.74 BCL2A1 (0.33)
SCHEMBL6703631 0.73 BCAT2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956283-B1 SUBSTITUTED PHENYLTRIAZOLIN(THI)ONES AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2003-06-11 EP disclosed
US-6350720-B2 CONTROLLING WEEDS BAYER AKTIENGESELLSCHAFT (DE) 2002-02-26 US disclosed
US-20010009887-A1 SUBSTITUTED PHENYLTRIAZOLIN(THI)ONES AND THEIR USE AS HERBICIDES BAKER AKTIENGESELLSCHAFT (DE) 2001-07-26 US disclosed
EP-0956283-A1 SUBSTITUTED PHENYLTRIAZOLIN(THI)ONES AND THEIR USE AS HERBICIDES BAYER AG (DE) 1999-11-17 EP disclosed
WO-1998032746-A1 SUBSTITUTED PHENYLTRIAZOLIN(THI)ONES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010009887-A1 SUBSTITUTED PHENYLTRIAZOLIN(THI)ONES AND THEIR USE AS HERBICIDES CYP2B6, CYP2D6, CYP2A6 DHODH 835/4885L3MBTL1 1632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.