Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.43 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7953858 | 0.99 | ITGB3 (0.47) | ITGB3ITGA2BGPR139ITGAVITGB5 | |
| Hydrochloric Acid SCHEMBL7943692 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| Hydrochloric Acid SCHEMBL7951859 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| Hydrochloric Acid SCHEMBL7943472 | 0.89 | ROCK2 (0.44) | ITGB3ITGA2BGPR139MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7950007 | 0.87 | POLB (0.49) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| Hydrochloric Acid SCHEMBL7950058 | 0.85 | LMNA (0.44) | ITGB3ITGA2BMEN1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7955879 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BF2R | |
| Hydrochloric Acid SCHEMBL7951937 | 0.81 | ITGB3 (0.58) | ITGB3ITGA2BF2R | |
| Hydrochloric Acid SCHEMBL7950049 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BITGAVITGB5ITGB6 | |
| SCHEMBL6964089 | 0.81 | ITGB3 (0.58) | ITGB3ITGA2BITGAVITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |