SCHEMBL6974536

SCHEMBL6974536

CCCCCC[C@H](F)CO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
MAPT P10636 2/20 0.50
CYP2D6 P10635 2/20 0.48
SPHK1 Q9NYA1 2/20 0.48
GMNN O75496 1/20 0.48
POLB P06746 1/20 0.48
THPO P40225 1/20 0.48
MTOR P42345 1/20 0.48
BLM P54132 1/20 0.48
KDM4E B2RXH2 1/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CETP P11597 1/20 0.48
HTT P42858 1/20 0.48
UBE2N P61088 1/20 0.48
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50680 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL9238877 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL8379294 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL9243487 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL5597598 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL5597787 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL9242608 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL9240412 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL8580154 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL7461382 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11015120-B2 Low birefringence ferroelectric liquid crystal mixtures THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2021-05-25 US disclosed
US-20180216004-A1 LOW BIREFRINGENCE FERROELECTRIC LIQUID CRYSTAL MIXTURES THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-08-02 US disclosed
EP-0821719-B1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING & MFG (US) 2003-01-02 EP disclosed
EP-0944565-B1 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2002-07-31 EP disclosed
EP-0946477-B1 DERIVATIVES OF 9,9-DIFLUORO-9,10-DIHYDROPHENANTHRENE FOR LIQUID CRYSTAL MIXTURES AVENTIS RES & TECHNOLOGY GMBH (DE) 2002-07-31 EP disclosed
EP-0946473-B1 FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES AVENTIS RES & TECHNOLOGY GMBH (DE) 2002-07-31 EP disclosed
EP-0946513-B1 DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2002-01-30 EP disclosed
EP-0944690-B1 1,1,5,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2001-11-28 EP disclosed
EP-0946476-B1 5,7-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE THEREOF IN LIQUID CRYSTAL MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2001-11-21 EP disclosed
EP-0946474-B1 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2001-11-07 EP disclosed
WO-1990013611-A2 OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-11-15 WO disclosed
US-4963288-A Fluoroalkoxydiphenyl pyrimidine, liquid crystal composition and electro-optic element CHISSO CORPORATION (JP) 1990-10-16 US disclosed
EP-0357739-A1 CHIRAL DERIVATIVES OF 1,2-DIFLUOROBENZENE MERCK PATENT GmbH (DE) 1990-03-14 EP disclosed
EP-0355772-A2 Liquid-crystalline copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-02-28 EP disclosed
WO-1989008639-A1 CHIRAL DERIVATIVES OF 1,2-DIFLUOROBENZENE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
EP-0332025-A1 Chiral derivatives of 1,2-difluorobenzenes MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
EP-0310081-A2 A ferroelectric liquid-crystalline polymeric composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-04-05 EP disclosed
US-4818807-A Liquid-crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1989-04-04 US disclosed
EP-0278665-A2 2-Substituted-alkyl ether and liquid crystal composition Chisso Corporation (JP) 1988-08-17 EP disclosed
EP-0258898-A2 Liquid-crystalline polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-03-09 EP disclosed