Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50680 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL9238877 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL8379294 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL9243487 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL5597598 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL6974536 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL9242608 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL9240412 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL8580154 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL7461382 | 1.00 | LMNA (0.58) | LMNAMAPTCYP2D6SPHK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265249-B2 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-09-04 | — | — | US | disclosed |
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-08-24 | — | — | US | disclosed |
| EP-0424099-B1 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORP (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5346978-A | Polymeric compositions useful in oxygen permeable contact lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5177168-A | Copolymer of an unsaturated carboxylic acid ester | POLYMER TECHNOLOGY CORP. (US) | 1993-01-05 | — | — | US | disclosed |
| US-5032658-A | Hardness, unsaturated ester | POLYMER TECHNOLOGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0424099-A2 | Method of Preparing Polymeric Compositions for Oxygen Permeable Contact Lenses | POLYMER TECHNOLOGY CORPORATION (US) | 1991-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | ALDH3A1, ALDH1A1, POLL | LMNA 1309/4885MAPT 3645/4885CYP2D6 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.