SCHEMBL50680

SCHEMBL50680

CCCCCCC(F)CO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
MAPT P10636 2/20 0.50
CYP2D6 P10635 2/20 0.48
SPHK1 Q9NYA1 2/20 0.48
GMNN O75496 1/20 0.48
POLB P06746 1/20 0.48
THPO P40225 1/20 0.48
MTOR P42345 1/20 0.48
BLM P54132 1/20 0.48
KDM4E B2RXH2 1/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CETP P11597 1/20 0.48
HTT P42858 1/20 0.48
UBE2N P61088 1/20 0.48
ALDH1A1 P00352 2/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9238877 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL8379294 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL9243487 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL5597598 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL6974536 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL5597787 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL9242608 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL9240412 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL8580154 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN
SCHEMBL7461382 1.00 LMNA (0.58) LMNAMAPTCYP2D6SPHK1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1098 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260910-B1 3,6-DIPHENYLPYRIDAZINES Chisso Corporation (JP) 1992-05-27 EP claimed
JP-63088161-A None JP disclosed
US-12031079-B2 Polymerisable LC medium and polymer film with flat optical dispersion MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
CN-113039659-B Self-assembled monolayers for electrode modification and devices comprising such self-assembled monolayers 默克专利有限公司 2024-07-05 CN disclosed
EP-4015598-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2024-05-22 EP disclosed
EP-3704176-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2024-05-15 EP disclosed
US-11958819-B2 Compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US disclosed
EP-3794650-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2024-03-13 EP disclosed
EP-3994234-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2024-02-21 EP disclosed
WO-2024017812-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-01-25 WO disclosed
US-4798680-A 2-FLUORO-1-ALKANOL CANON KABUSHIKI KAISHA (JP) 1989-01-17 US disclosed
EP-0278665-A2 2-Substituted-alkyl ether and liquid crystal composition Chisso Corporation (JP) 1988-08-17 EP disclosed
EP-0274128-A2 Liquid-crystalline polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-07-13 EP disclosed
EP-0269963-A2 Ferroelectric liquid crystals F. HOFFMANN-LA ROCHE AG (CH) 1988-06-08 EP disclosed
JP-S6388161-A FLUOROALKANE DERIVATIVE CANON INC 1988-04-19 JP disclosed
EP-0260910-A1 3,6-Diphenylpyridazines Chisso Corporation (JP) 1988-03-23 EP disclosed
EP-0260153-A2 Cyclohexylphenylpyridazines Chisso Corporation (JP) 1988-03-16 EP disclosed
EP-0258898-A2 Liquid-crystalline polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-03-09 EP disclosed
EP-0237007-A2 Fluoroalkane derivative and liquid crystal composition CANON KABUSHIKI KAISHA (JP) 1987-09-16 EP disclosed
US-4255594-A Hydrogenation of halogen-containing carboxylic anhydrides ALLIED CHEMICAL CORPORATION (US) 1981-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958819-B2 Compounds for optically active devices PDE6C, ALDH1A2, PDE6A LMNA 3184/4885MAPT 490/4885CYP2D6 2252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.