Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17772058 | 0.86 | ALOX15 (0.55) | KDM4EALOX15LMNAMEN1GAA | |
| SCHEMBL11341702 | 0.83 | PI4KA (0.53) | KDM4EALOX15LMNAMEN1KMT2A | |
| SCHEMBL10756157 | 0.83 | POLB (0.54) | KDM4ELMNAMEN1GAAKMT2A | |
| Bromide SCHEMBL11334286 | 0.81 | POLB (0.52) | KDM4ELMNAMEN1GAAKMT2A | |
| SCHEMBL24150006 | 0.79 | PIK3CD (0.47) | KDM4EALOX15LMNAMEN1GAA | |
| SCHEMBL172718 | 0.79 | HSD17B1 (0.51) | KDM4ELMNAPOLBCYP1A2CCR1 | |
| SCHEMBL6506946 | 0.79 | KDM4E (0.50) | KDM4EALOX15LMNAALDH1A1MAPT | |
| SCHEMBL3027291 | 0.79 | NPC1 (0.50) | KDM4EALOX15LMNAMEN1KMT2A | |
| Bromide SCHEMBL17744696 | 0.77 | HSD17B1 (0.50) | KDM4ELMNAPOLBCYP1A2CCR1 | |
| SCHEMBL30596191 | 0.77 | BACE1 (0.50) | KDM4ELMNAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708769-B1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AG (DE) | 2003-01-29 | — | — | EP | claimed |
| EP-0708769-A1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | claimed |
| WO-1995002590-A2 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | claimed |
| CN-1127507-A | Substituted 2-fused phenylpyridines with herbicidal activity | BASF AG (DE) | 1996-07-24 | — | — | CN | disclosed |
| US-4366319-A | Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones | STERLING DRUG INC. (US) | 1982-12-28 | — | — | US | disclosed |
| US-4310531-A | 5-(Pyridinyl)-benzoxazol-2(3H)-ones and their use as cardiotonics | STERLING DRUG INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4297363-A | 2-Amino-3(4 or 5)-(pyridinyl)phenols and their use as cardiotonics | STERLING DRUG INC. (US) | 1981-10-27 | — | — | US | disclosed |