SCHEMBL697542

SCHEMBL697542

OC(c1ncc[nH]1)c1cccc(C(F)(F)F)c1F

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698030 0.85 F2RL1 (0.52) F2RL1
SCHEMBL698140 0.83 ADRA2A (0.53) F2RL1
SCHEMBL714299 0.82 F2RL1 (0.59) F2RL1
SCHEMBL954936 0.80 TAAR1 (0.44) F2RL1
SCHEMBL7235096 0.75 TAAR1 (0.49)
SCHEMBL696418 0.74 F2RL1 (0.61) F2RL1
SCHEMBL697155 0.73 ADRA2A (0.55) F2RL1
SCHEMBL2472106 0.72 TAAR1 (0.43) F2RL1
SCHEMBL696107 0.72 ADRA2A (0.57) F2RL1
SCHEMBL697237 0.71 P2RX7 (0.52) F2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423199-A1 Substituted imidazoles and their use as pesticides Pfizer Limited (GB) 2012-02-29 EP disclosed
CN-101370786-B Substituted imidazoles and their use as pesticides PFIZER 2012-01-11 CN disclosed
EP-1981853-B1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES PFIZER LTD (GB) 2011-04-13 EP disclosed
CN-101370786-A Substituted imidazoles and their use as pesticides PFIZER LTD (GB) 2009-02-18 CN disclosed