SCHEMBL698030

SCHEMBL698030

OC(c1ncc[nH]1)c1cccc(C(F)(F)F)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 18/20 0.52
P2RX7 Q99572 1/20 0.46
TAAR1 Q96RJ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL697542 0.85 F2RL1 (0.49) F2RL1
SCHEMBL697237 0.84 P2RX7 (0.52) F2RL1P2RX7TAAR1
SCHEMBL714299 0.73 F2RL1 (0.59) F2RL1
SCHEMBL697155 0.72 ADRA2A (0.55) F2RL1P2RX7TAAR1
SCHEMBL696107 0.71 ADRA2A (0.57) F2RL1P2RX7TAAR1
SCHEMBL2472106 0.71 TAAR1 (0.43) F2RL1TAAR1
SCHEMBL698140 0.71 ADRA2A (0.53) F2RL1P2RX7TAAR1
SCHEMBL696418 0.70 F2RL1 (0.61) F2RL1
SCHEMBL697429 0.70 P2RX7 (0.44) P2RX7TAAR1
SCHEMBL4074793 0.70 F2RL1 (0.55) F2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423199-A1 Substituted imidazoles and their use as pesticides Pfizer Limited (GB) 2012-02-29 EP disclosed
EP-1981853-B1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES PFIZER LTD (GB) 2011-04-13 EP disclosed