Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GNG2 | P59768 | 1/20 | 0.36 |
| ▸ | GNB1 | P62873 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779070 | 0.95 | ATM (0.41) | ATMMAPTALDH1A1HPGDTSHR | |
| SCHEMBL10687927 | 0.91 | ATM (0.44) | ATMMAPTALDH1A1HPGDTSHR | |
| SCHEMBL10691604 | 0.88 | HPGD (0.44) | MAPTALDH1A1HPGDCTNNB1WNT3A | |
| SCHEMBL10688073 | 0.86 | HSD17B3 (0.45) | CTNNB1WNT3ASIGMAR1 | |
| SCHEMBL10693207 | 0.85 | GNG2 (0.45) | MAPTALDH1A1CTNNB1WNT3AGNG2 | |
| SCHEMBL7084031 | 0.85 | HSD17B3 (0.47) | ATMMAPTALDH1A1CTNNB1WNT3A | |
| SCHEMBL8102062 | 0.84 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDCTNNB1WNT3A | |
| SCHEMBL27534622 | 0.83 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4694745 | 0.83 | MAPT (0.47) | MAPTALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL8071531 | 0.82 | ALDH1A1 (0.36) | MAPTALDH1A1HPGDCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791104-A | HYPOTENSIVE, ANTILIPEMIC, ANTIHROMBOTIC, ANTIHYPOXIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1988-12-13 | — | — | US | disclosed |
| US-4638070-A | HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1987-01-20 | — | — | US | disclosed |