Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 8/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971904 | 0.81 | CTSS (0.52) | CTSSCTSLCTSC | |
| Hydrochloric Acid SCHEMBL5367945 | 0.80 | CTSS (0.51) | CTSSCTSLCTSC | |
| SCHEMBL7007715 | 0.79 | CTSS (0.39) | CTSSCTSKCTSLCTSBSIGMAR1 | |
| SCHEMBL5363252 | 0.77 | CTSS (0.60) | CTSSCTSLCTSC | |
| SCHEMBL7005820 | 0.76 | CTSS (0.38) | CTSSCTSKCTSLCTSBCTSC | |
| SCHEMBL5366656 | 0.72 | CTSS (0.49) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5364829 | 0.70 | CTSS (0.43) | CTSSCTSKCTSL | |
| SCHEMBL5356456 | 0.70 | CTSS (0.62) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5364783 | 0.69 | CTSS (0.49) | CTSSCTSLCTSC | |
| SCHEMBL5361059 | 0.69 | CTSS (0.60) | CTSSCTSLCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | disclosed |