Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831609 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KDM4EHTTF2F10 | |
| SCHEMBL4831634 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KDM4EHTTF2F10 | |
| SCHEMBL4831561 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KDM4EHTTF2F10 | |
| SCHEMBL6349166 | 0.81 | GABBR2 (0.34) | TSHRLMNACYP2D6CYP3A4KMT2A | |
| SCHEMBL6955213 | 0.78 | MMP8 (0.36) | KDM4ETSHRLMNAMAPTALOX15 | |
| SCHEMBL3958590 | 0.70 | GAA (0.41) | ALDH1A1KDM4ETSHRMAPTALOX15 | |
| SCHEMBL5929582 | 0.70 | ALDH1A1 (0.31) | ALDH1A1HTTMAPT | |
| SCHEMBL5160963 | 0.70 | ALDH1A1 (0.31) | ALDH1A1HTTMAPT | |
| SCHEMBL7180513 | 0.69 | CYP4F2 (0.36) | ALDH1A1KDM4ETSHRLMNAMAPT | |
| SCHEMBL2320013 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTF2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0630366-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. Searle & Co. (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1993008164-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |