Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17973359 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL649287 | 0.87 | KMT2A (0.55) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL8823334 | 0.87 | KMT2A (0.55) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL2625198 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| Biphenyl SCHEMBL28073453 | 0.83 | PTGS2 (0.61) | SMN1; SMN2ALDH1A1MAPTPTGS2PDCD1 | |
| Biphenyl SCHEMBL1774586 | 0.83 | PTGS2 (0.61) | SMN1; SMN2ALDH1A1MAPTPTGS2PDCD1 | |
| SCHEMBL7635145 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL8995348 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| Alcohol SCHEMBL28915598 | 0.80 | PGR (0.55) | SMN1; SMN2LMNAHTTALDH1A1MAPT | |
| SCHEMBL1928398 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134733-A1 | TREATMENT OF SIGNS, SYMPTOMS AND/OR COMPLICATIONS OF VIRAL, BACTERIAL, PROTOZOAL, AND/OR FUNGAL INFECTIONS BY HIGH PENETRATION PRODRUGS | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-07-20 | — | — | WO | disclosed |
| EP-1109560-B1 | COMPOUNDS USEFUL AS AICARFT INHIBITORS | AGOURON PHARMA (US) | 2003-08-27 | — | — | EP | disclosed |
| US-6525050-B1 | Inhibit the enzyme aminoimidazole carboxamide ribonucleotide formyl transferase; antiproliferative agents; antitumor, antiinflammatory, antipsoriatic, and/or immunosuppressive | AGOURON PHARMACEUTICALS, INC. | 2003-02-25 | — | — | US | disclosed |
| EP-1109560-A4 | COMPOUNDS USEFUL AS AICARFT INHIBITORS | AGOURON PHARMA (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-1109560-A1 | COMPOUNDS USEFUL AS AICARFT INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000013688-A1 | COMPOUNDS USEFUL AS AICARFT INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |
| US-4518608-A | INDOMETHALIN WITH HYDROPHILIC COMPOUND FOR PARENTERAL ADMINISTRATION | MEDIMPEX GYOGYSZERKUELKERESKEDELMI VAALLALAT (HU) | 1985-05-21 | — | — | US | disclosed |