Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.70 |
| ▸ | ITGAV | P06756 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085479 | 1.00 | ITGB3 (0.70) | ITGB3ITGA2BITGAVCYP3A4SUCNR1 | |
| SCHEMBL7352353 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL7344449 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL7086286 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BCYP3A4 | |
| SCHEMBL7086294 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BCYP3A4 | |
| SCHEMBL9558976 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL7391723 | 0.85 | ITGB3 (0.79) | ITGB3ITGA2BITGAVSUCNR1 | |
| SCHEMBL6978255 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7972452 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BITGAV | |
| SCHEMBL9558988 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0630366-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. Searle & Co. (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1993008164-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |