Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SREBF2 | Q12772 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225043 | 0.88 | RAB9A (0.49) | LTA4HRAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2225564 | 0.88 | RAB9A (0.54) | LTA4HRAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2225642 | 0.87 | ALDH1A1 (0.51) | LTA4HRAB9AALDH1A1NPC1MAPT | |
| SCHEMBL14672183 | 0.86 | LTA4H (0.46) | LTA4HRAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2225700 | 0.85 | LTA4H (0.55) | LTA4HALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL12282550 | 0.81 | RAB9A (0.54) | LTA4HRAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2225766 | 0.78 | MEN1 (0.39) | LTA4HRAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL16217968 | 0.75 | RAB9A (0.65) | LTA4HRAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL231094 | 0.73 | LTA4H (0.80) | LTA4HRAB9AALDH1A1NPC1MAPT | |
| Bromide SCHEMBL8360772 | 0.72 | LTA4H (0.77) | LTA4HRAB9AALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |