Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | STS | P08842 | 4/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098572 | 0.85 | MEN1 (0.53) | MEN1KMT2AGPR119USP30JAK2 | |
| SCHEMBL30936573 | 0.85 | MEN1 (0.53) | MEN1KMT2AGPR119USP30JAK2 | |
| SCHEMBL69078 | 0.85 | GPR119 (0.51) | MEN1KMT2AGPR119USP30JAK2 | |
| SCHEMBL69603 | 0.84 | MEN1 (0.52) | MEN1KMT2AGPR119USP30JAK2 | |
| SCHEMBL2792425 | 0.82 | MEN1 (0.60) | MEN1KMT2ASTSGPR119USP30 | |
| SCHEMBL6155105 | 0.82 | GPR119 (0.57) | MEN1KMT2AGPR119USP30 | |
| SCHEMBL27833476 | 0.82 | OPRM1 (0.46) | MEN1KMT2A | |
| SCHEMBL30936645 | 0.81 | USP30 (0.47) | MEN1KMT2AGPR119USP30JAK2 | |
| SCHEMBL11164437 | 0.81 | USP30 (0.47) | MEN1KMT2AGPR119USP30JAK2 | |
| SCHEMBL25388020 | 0.80 | MEN1 (0.53) | MEN1KMT2ASTSGPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129376-B2 | Piperidine derivatives as inhibitors of stearoyl-CoA desaturase | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-03-06 | — | — | US | disclosed |
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | MEN1 4884/4885KMT2A 1352/4885STS 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.