Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976565 | 1.00 | NOS1 (0.42) | NOS1NOS3NOS2 | |
| SCHEMBL4395139 | 0.91 | NOS3 (0.41) | NOS1NOS3NOS2 | |
| SCHEMBL4395142 | 0.91 | NOS3 (0.41) | NOS1NOS3NOS2 | |
| SCHEMBL6974702 | 0.81 | NR1H4 (0.40) | — | |
| SCHEMBL4398421 | 0.81 | NOS3 (0.60) | NOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL4393258 | 0.80 | NOS3 (0.59) | NOS1NOS3NOS2 | |
| SCHEMBL4399979 | 0.79 | NOS1 (0.54) | NOS1NOS3NOS2 | |
| SCHEMBL4399977 | 0.79 | NOS1 (0.54) | NOS1NOS3NOS2 | |
| Iodide SCHEMBL4393546 | 0.78 | NOS1 (0.54) | NOS1NOS3NOS2 | |
| Iodide SCHEMBL4393544 | 0.78 | NOS1 (0.54) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653312-B1 | Such as 3-((3-((amino(2-thienyl)methylideneamino)-benzyl)-amino)-N-(1- methyl-2,3-dihydro-1H-indol-5-yl)propanamide; NO-synthase enzyme inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-11-25 | — | — | US | disclosed |
| EP-1318149-A1 | Amidine derivatives, their preparation and application as medicines and pharmaceutical compositions containing them | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-06-11 | — | — | EP | disclosed |
| EP-1115719-B1 | NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOD CONSEILS RECH APPLIC (FR) | 2003-03-05 | — | — | EP | disclosed |