Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227206 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTSCN5AKMT2A | |
| SCHEMBL27710646 | 0.86 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8491361 | 0.84 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTKMT2ASIGMAR1 | |
| SCHEMBL11122002 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MAPTHRH3TSHRSMN1; SMN2 | |
| SCHEMBL14227975 | 0.83 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6614327 | 0.80 | CYP3A4 (0.48) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11755100 | 0.78 | ALDH1A1 (0.71) | ALDH1A1POLBMAPTKMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL9766013 | 0.77 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL9200146 | 0.76 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTKMT2ATSHR | |
| SCHEMBL7374163 | 0.76 | HRH3 (0.58) | ALDH1A1SCN5AKMT2AHRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296949-A2 | PIPERIDINE AMIDES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001098268-A2 | PIPERIDINE AMIDES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |