Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | DRD1 | P21728 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.66 |
| ▸ | DRD3 | P35462 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976684 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HRH3TSHRSMN1; SMN2MAPT | |
| Pipamperone SCHEMBL2412 | 0.80 | HTR1A (1.00) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL6621425 | 0.80 | HTR1A (1.00) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL10533161 | 0.79 | HTR1A (0.98) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL364623 | 0.79 | HTR1A (0.98) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL647930 | 0.79 | HTR1A (0.98) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL14696833 | 0.79 | HTR1A (0.98) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL8764867 | 0.79 | HTR1A (0.98) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL4671026 | 0.79 | HTR1A (0.98) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 | |
| Pipamperone SCHEMBL8327319 | 0.78 | HTR1A (0.96) | ALDH1A1HTR1AADRA2ADRD1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125046-A1 | Process for preparing pyrimidinetrione derivatives | SAPOS S.A. (CH) | 1984-11-14 | — | — | EP | disclosed |