Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3172041 | 0.77 | MAPT (0.57) | GPR119KDM4EPKMPTPN2PTPN1 | |
| SCHEMBL6984087 | 0.76 | GPR119 (0.51) | GPR119KDM4EPKMSYK | |
| SCHEMBL5248569 | 0.76 | KDM4E (0.55) | GPR119KDM4EPKMALDH1A1PTPN2 | |
| SCHEMBL6981257 | 0.76 | FAAH (0.46) | GPR119KDM4EPKMSYKALDH1A1 | |
| SCHEMBL4773996 | 0.76 | GPR119 (0.51) | GPR119KDM4EPKM | |
| SCHEMBL1405373 | 0.76 | KDM4E (0.57) | GPR119KDM4EPKMPTPN2PTPN1 | |
| SCHEMBL8386605 | 0.76 | KDM4E (0.63) | GPR119KDM4EPKMALDH1A1PTPN2 | |
| SCHEMBL3582211 | 0.75 | EPHX2 (0.55) | GPR119KDM4EPKMALDH1A1 | |
| SCHEMBL4500201 | 0.75 | GPR119 (0.52) | GPR119KDM4EPKMPTPN2PTPN1 | |
| SCHEMBL16825244 | 0.75 | GPR119 (0.60) | GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839145-B1 | HETEROCYCLYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO KG (DE) | 2003-11-05 | — | — | EP | disclosed |