Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984087 | 0.78 | GPR119 (0.51) | FAAHGPR119KDM4EPKMSYK | |
| SCHEMBL21607886 | 0.77 | ALOX5AP (0.52) | FAAHGPR119KDM4EPKMSLC2A1 | |
| SCHEMBL6976858 | 0.76 | GPR119 (0.48) | GPR119KDM4EPKMSYKALDH1A1 | |
| SCHEMBL7274954 | 0.76 | GPR119 (0.51) | FAAHGPR119KDM4EPKMSLC2A1 | |
| SCHEMBL4665126 | 0.75 | GPR119 (0.52) | FAAHGPR119KDM4EPKMALOX5AP | |
| SCHEMBL18228507 | 0.75 | GPR119 (0.53) | FAAHGPR119KDM4EPKMALOX5AP | |
| SCHEMBL4036422 | 0.74 | GPR119 (0.54) | FAAHGPR119KDM4EPKMSLC2A1 | |
| SCHEMBL6979526 | 0.74 | POLB (0.52) | FAAHGPR119KDM4EPKMSYK | |
| SCHEMBL23119230 | 0.74 | KDM4E (0.55) | GPR119KDM4EPKMALDH1A1 | |
| SCHEMBL8601284 | 0.73 | GPR119 (0.53) | FAAHGPR119KDM4EPKMALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839145-B1 | HETEROCYCLYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | ABBOTT GMBH & CO KG (DE) | 2003-11-05 | — | — | EP | disclosed |