Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697381 | 0.86 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL698194 | 0.84 | KMT2A (0.46) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL5851274 | 0.81 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL1345858 | 0.77 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL697005 | 0.75 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL697274 | 0.75 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL24826220 | 0.74 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL696380 | 0.74 | OPRD1 (0.52) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL30301935 | 0.74 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13389039 | 0.74 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |