Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5851274 | 0.87 | RAB9A (0.53) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL699131 | 0.85 | KMT2A (0.41) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL697690 | 0.84 | RAB9A (0.51) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL697631 | 0.82 | RAB9A (0.46) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL696380 | 0.82 | OPRD1 (0.52) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24826220 | 0.80 | RAB9A (0.48) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30301935 | 0.80 | RAB9A (0.48) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL418384 | 0.76 | RAB9A (0.57) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL697274 | 0.76 | RAB9A (0.49) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL697005 | 0.76 | RAB9A (0.49) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |