SCHEMBL6976915

SCHEMBL6976915

CCOC(=O)Oc1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
KMT2A Q03164 3/20 0.48
ALOX5 P09917 1/20 0.48
MAPT P10636 4/20 0.48
MEN1 O00255 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP1A2 P05177 1/20 0.46
GAA P10253 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
CYP2C19 P33261 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TARBP2 Q15633 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6432240 0.92 SOAT1 (0.48) NPC1RAB9AKMT2AALOX5MAPT
SCHEMBL37520 0.89 MAPT (0.56) NPC1RAB9AKMT2AALOX5MAPT
SCHEMBL6451238 0.87 ALDH1A1 (0.55) RAB9AKMT2AMAPTMEN1SMN1; SMN2
SCHEMBL17473107 0.86 ALOX5 (0.51) NPC1RAB9AKMT2AALOX5MAPT
SCHEMBL6633777 0.86 CA12 (0.50) KMT2AMEN1SMN1; SMN2KDM4EALDH1A1
SCHEMBL1157298 0.85 TSHR (0.51) ALOX5TDP1ALDH1A1TP53HSD17B10
SCHEMBL6228591 0.84 HRH2 (0.48) NPC1RAB9AKMT2AMAPTMEN1
SCHEMBL27861489 0.83 MAPT (0.54) NPC1RAB9AKMT2AMAPTMEN1
SCHEMBL862441 0.83 KMT2A (0.46) NPC1RAB9AKMT2AMAPTMEN1
SCHEMBL233643 0.82 KMT2A (0.55) NPC1RAB9AKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3838892-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2022-10-12 EP disclosed
EP-3293173-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2021-07-28 EP disclosed
EP-3838892-A1 METHOD FOR PRODUCING ISOCYANATE Asahi Kasei Kabushiki Kaisha (JP) 2021-06-23 EP disclosed
EP-2980066-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2021-04-21 EP disclosed
EP-3293173-A1 METHOD FOR PRODUCING ISOCYANATE Asahi Kasei Kabushiki Kaisha (JP) 2018-03-14 EP disclosed
US-9714215-B2 Method for producing isocyanate ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-07-25 US disclosed
US-20160052874-A1 METHOD FOR PRODUCING ISOCYANATE ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-02-25 US disclosed
EP-2980066-A1 METHOD FOR PRODUCING ISOCYANATE Asahi Kasei Chemicals Corporation (JP) 2016-02-03 EP disclosed
CN-1217903-C Substituted biphenyl oxazoline BAYER AG (DE) 2005-09-07 CN disclosed
EP-0861239-B1 BIPHENYL ETHER OXAZOLINES AND THEIR USE AS PEST-CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2003-02-12 EP disclosed
US-6211214-B1 PESTICIDES, INSECTICIDES OR MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
US-6172093-B1 PESTICIDES, INSECTICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
EP-0980361-A1 SUBSTITUTED DIPHENYL OXAZOLIN DERIVATIVES WITH INSECTICIDAL EFFECT BAYER AG (DE) 2000-02-23 EP disclosed
US-5969147-A Substituted biphenyloxazolines BAYER AKTIENGESELLSCHAFT (DE) 1999-10-19 US disclosed
EP-0696584-B1 Substituted biphenyloxazolines and their use as fungicides BAYER AG (DE) 1999-01-20 EP disclosed
WO-1998047881-A1 SUBSTITUTED DIPHENYL OXAZOLIN DERIVATIVES WITH INSECTICIDAL EFFECT BAYER AKTIENGESELLSCHAFT (DE) 1998-10-29 WO disclosed
EP-0861239-A1 BIPHENYL ETHER OXAZOLINES AND THEIR USE AS PEST-CONTROL AGENTS BAYER AG (DE) 1998-09-02 EP disclosed
WO-1997019067-A1 BIPHENYL ETHER OXAZOLINES AND THEIR USE AS PEST-CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-05-29 WO disclosed
CN-1122801-A Substituted biphenyl oxazolines BAYER AG (DE) 1996-05-22 CN disclosed
EP-0696584-A1 Substituted biphenyloxazolines and their use as fungicides BAYER AG (DE) 1996-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160052874-A1 METHOD FOR PRODUCING ISOCYANATE CPS1, ALKBH3, IDH3A NPC1 553/4885RAB9A 4158/4885KMT2A 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.