SCHEMBL862441

SCHEMBL862441

CCOC(=O)Oc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.44
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
NPSR1 Q6W5P4 2/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP14 P50281 1/20 0.43
MEN1 O00255 2/20 0.42
HPGD P15428 1/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37520 0.86 MAPT (0.56) KMT2ARAB9ANPC1ALDH1A1MAPT
SCHEMBL279314 0.84 KMT2A (0.51) KMT2AALDH1A1MAPTATMTDP1
SCHEMBL279037 0.84 KMT2A (0.51) KMT2ARAB9ANPC1ALDH1A1MAPT
SCHEMBL6451238 0.84 ALDH1A1 (0.55) KMT2ARAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL11977353 0.83 ALDH1A1 (0.44) KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL279599 0.83 KMT2A (0.48) KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL279173 0.83 KMT2A (0.48) KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL6976915 0.83 NPC1 (0.51) KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL279035 0.81 RAB9A (0.41) KMT2ARAB9AALDH1A1MAPTL3MBTL1
SCHEMBL279026 0.81 KMT2A (0.48) KMT2AALDH1A1MAPTATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142969-B2 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-03-27 US disclosed
US-8142969-B2 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-03-27 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-7887981-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers, a photosensitive layer and protective coatings comprising curable resins; durability FUJI XEROX CO., LTD. (JP) 2011-02-15 US disclosed
US-7887981-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers, a photosensitive layer and protective coatings comprising curable resins; durability FUJI XEROX CO., LTD. (JP) 2011-02-15 US disclosed
US-7842444-B2 comprising phenolic resin; a charge transportable material having aryl tertiary amine reactive functional group; and para-toluenesulfonic acid; free of image defects; high image quality; mechanical strength FUJI XEROX CO., LTD. (JP) 2010-11-30 US disclosed
US-7842444-B2 comprising phenolic resin; a charge transportable material having aryl tertiary amine reactive functional group; and para-toluenesulfonic acid; free of image defects; high image quality; mechanical strength FUJI XEROX CO., LTD. (JP) 2010-11-30 US disclosed
US-20080273897-A1 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2008-11-06 US disclosed
US-20080273897-A1 Electrophotographic photoreceptor, process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2008-11-06 US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed
US-20080102390-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed
US-20080102390-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed