Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726652 | 0.87 | PKM (0.34) | GAAPDE2APDE10APKMPKLR | |
| SCHEMBL7526323 | 0.83 | PDE2A (0.34) | GAAPDE2APDE10APTGESLMNA | |
| SCHEMBL953998 | 0.83 | CSNK1D (0.35) | PDE2APDE10APTGESLMNAMAPT | |
| SCHEMBL5726912 | 0.82 | NR1H2 (0.36) | PDE2APDE10APTGESMAPTMAPK1 | |
| SCHEMBL6073454 | 0.82 | PDE2A (0.33) | GAAPDE2APDE10APTGESLMNA | |
| SCHEMBL5726642 | 0.82 | PDE2A (0.33) | GAAPDE2APDE10APTGESLMNA | |
| SCHEMBL5727053 | 0.82 | PDE2A (0.33) | GAAPDE2APDE10APTGESLMNA | |
| SCHEMBL5727601 | 0.81 | PTGES (0.39) | GAAPDE2APDE10APTGESNR1H2 | |
| SCHEMBL6972041 | 0.81 | PDE2A (0.34) | GAAPDE2APDE10APTGESLMNA | |
| SCHEMBL2933280 | 0.81 | PDE2A (0.34) | GAAPDE2APDE10APTGESLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123290-B1 | 3-(SUBSTITUTED PHENYL)-5-THIENYL-1,2,4-TRIAZOLE COMPOUNDS WITH ACTIVITY AGAINST WHITEFLY | DOW AGROSCIENCES LLC (US) | 2003-02-19 | — | — | EP | disclosed |
| US-6265424-B1 | INSECTICIDES, MITICIDES | DOW AGROSCIENCES LLC | 2001-07-24 | — | — | US | disclosed |