Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976971 | 0.87 | GAA (0.35) | PKMPKLRNR1H2NR1H3PDE2A | |
| SCHEMBL5727655 | 0.82 | NR1H2 (0.37) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL5727601 | 0.81 | PTGES (0.39) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL7526323 | 0.81 | PDE2A (0.34) | NR1H2NR1H3NPC1RAB9APDE2A | |
| SCHEMBL5726786 | 0.78 | PTGES (0.37) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL5726642 | 0.78 | PDE2A (0.33) | NR1H2NR1H3NPC1RAB9APDE2A | |
| SCHEMBL6073454 | 0.78 | PDE2A (0.33) | NR1H2NR1H3NPC1RAB9APDE2A | |
| SCHEMBL5727053 | 0.78 | PDE2A (0.33) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL5726494 | 0.77 | HSD17B2 (0.40) | NR1H2NR1H3NPC1RAB9AHSD17B2 | |
| SCHEMBL5727234 | 0.77 | TDP2 (0.41) | NR1H2NR1H3F2RL3MAPTPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425278-B1 | INSECTICIDAL 3-(2,6-DISUBSTITUTED PHENYL)-5- 4- OR 5-ARYLTHIEN-2- OR -3-YL|-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2006-12-20 | — | — | EP | disclosed |
| US-7056940-B2 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-2-yl]-1,2,4-triazoles | DOW AGROSCIENCES LLC (US) | 2006-06-06 | — | — | US | disclosed |
| US-6949576-B2 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-3-yl]-1,2,4-triazoles | DOW AGROSCIENCES LLC (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040171661-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-2-yl]-1,2,4-triazoles | HEGDE VIDYADHAR BABU (US) | 2004-09-02 | — | — | US | disclosed |
| US-6770665-B2 | TRIAZOLE COMPOUNDS HAVING A 2,6-DISUBSTITUTED-PHENYL GROUP IN THE 3-POSITION, ARYLTHIEN-2- OR -3-YL IN THE 5-POSITION AND AN ALKYL GROUP IN THE 1-POSITION ARE EFFECTIVE IN CONTROLLING LEPIDOPTERA, COLEOPTERA, MITES AND OTHER SUCKING PESTS. | DOW AGROSCIENCES LLC | 2004-08-03 | — | — | US | disclosed |
| US-20040072887-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-3-yl]-1,2,4-triazoles | HEGDE VIDYADHAR BABU (US) | 2004-04-15 | — | — | US | disclosed |
| US-20030134748-A1 | Insecticial 3-(2,6-disubstituted phenyl)-5-[4- or 5-arylthien-2- or -3-yl]-1,2,4-triazoles | DOW AGROSCIENCES LLC | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171661-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-2-yl]-1,2,4-triazoles | L3MBTL3, API5, L3MBTL4 | PKM 3399/4885PKLR 4510/4885NR1H2 4351/4885 |
| US-20040072887-A1 | Insecticidal 3-(2,6-disubstituted phenyl)-5-[5-arylthien-3-yl]-1,2,4-triazoles | L3MBTL3, API5, L3MBTL4 | PKM 3386/4885PKLR 4519/4885NR1H2 4371/4885 |
| US-20030134748-A1 | Insecticial 3-(2,6-disubstituted phenyl)-5-[4- or 5-arylthien-2- or -3-yl]-1,2,4-triazoles | L3MBTL3, API5, L3MBTL4 | PKM 3664/4885PKLR 4349/4885NR1H2 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.