Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14786250 | 0.82 | TAAR1 (0.48) | ERN1MAP4K4 | |
| SCHEMBL1125758 | 0.82 | ERN1 (0.50) | ERN1 | |
| SCHEMBL26083455 | 0.79 | ERN1 (0.62) | ERN1 | |
| SCHEMBL459167 | 0.79 | SRC (0.47) | ERN1 | |
| SCHEMBL5734212 | 0.79 | PTGS2 (0.41) | ERN1 | |
| SCHEMBL12225756 | 0.77 | ACHE (0.48) | PTPN5ACHEMAP4K4 | |
| SCHEMBL9901972 | 0.77 | ERN1 (0.50) | ERN1 | |
| SCHEMBL15344106 | 0.76 | ACHE (0.46) | PTPN5ACHEMAP4K4 | |
| SCHEMBL1312966 | 0.74 | CYP2A6 (0.52) | PTPN5ACHE | |
| SCHEMBL8264669 | 0.73 | HSD17B1 (0.65) | PTPN5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244446-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1244446-A1 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001039773-A1 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |